Top 25 GLP-1 FAQs. Rapid Fire Answers with Humor, Honesty, and Experience

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Because you deserve real answers, not robotic fine print or some of the random comments on social media! Check out our Top 25 GLP1 FAQs to get the information you need.

Top 25 GLP-1 FAQs

Welcome to the GLP-1 Hot Seat

Because you deserve real answers, not robotic fine print or some of the random comments on social media!

If I had a dollar for every time someone asked me, “Wait, so what does Mounjaro actually do?”, I’d have enough to pay for my next fill without insurance drama. Whether you are brand new to GLP-1s (like Mounjaro, Zepbound, Ozempic, or Wegovy) or just really deep in the Reddit rabbit hole, these are the top 25 questions I get asked the most, answered with the honesty of someone who’s actually injected this stuff into their stomach for 22 months, and the humor of someone who still doesn’t understand why my pants make that weird noise when I walk now.

Let’s get into it. Starting with the basics and then the good stuff! Stick with me here!

THE BASICS

1. What is a GLP-1 medication?
It’s a class of drugs that mimic a natural hormone to regulate blood sugar and reduce appetite. In plain English: it helps you feel full faster and for longer. And sometimes like you swallowed a balloon.

2. Is this the same thing as Ozempic?
Kind of! Ozempic is a GLP-1 (semaglutide). Mounjaro and Zepbound are dual agonists (tirzepatide) that also target GIP. Think of them as Ozempic’s overachieving cousins.

3. Are these just for diabetes?
Originally, yes. But they’re now FDA-approved for weight loss under different names (Wegovy for semaglutide, Zepbound for tirzepatide). Many use them “off-label” if insurance plays nice.

4. How does it help me lose weight?
By reducing appetite, slowing stomach emptying, and decreasing food “noise.” That inner voice yelling “nachos!” all day? GLP-1s hand it a muzzle.

5. Do I still need to diet?
You need to eat differently, not necessarily less. Protein, fiber, hydration, and smart choices still matter. And yes, you can still eat bread. Calm down, Carol.

SIDE EFFECTS & BODY STUFF

6. Why do I feel like I’ve been hit by a food truck?
Nausea is common at first. Eat slowly. Choose bland foods. Don’t test your luck with greasy tacos on week one. You’ve been warned.

7. Will I stop feeling sick eventually?
Most people adjust within a few weeks. If not, talk to your doc. Lowering your dose or using anti-nausea meds (hello, ginger everything) can help.

8. Why am I constipated all the time?
Because your stomach is slower and your hydration game is weak. Water, fiber, electrolytes, and… let’s be real… Miralax.

9. Is “Ozempic face” real?
Rapid weight loss can cause facial volume loss. It’s not the drug, it’s the fat. Moisturize, hydrate, and if it bugs you, fillers exist. Find a Dermatologist, yesterday!

10. Do you poop less?
You eat less. So yes, there’s less output. It’s math. Weird, Poop Math.

DOSING & DAILY LIFE

11. How often do I take it?
Usually once a week. Same day, same time. Injection day becomes a weird little ritual you never expected to care about.

12. Does it hurt?
Not really! Tiny needle. It’s over faster than the awkward pause when someone says “I liked you better before you lost weight.”

13. Where do you inject it?
Thigh, belly, or upper arm. Rotate sites. Avoid scars, tattoos, and anywhere you’ll immediately regret.

14. Can I still drink alcohol?
Yes, but you may not want to. Some report zero tolerance now. Others still enjoy wine. Just hydrate and be cautious. (Also, drunk-nausea on GLP-1s is… special.)

15. What if I forget a dose?
You usually have a few days to make it up. Check with your doctor and medical professional before you go rogue.

THE EMOTIONAL ROLLERCOASTER

16. Why do I feel weirdly sad sometimes?
Hormones. Fat stores estrogen. Losing weight affects your mood. Add in less comfort eating and BAM! Unexpected emotions. Therapy is underrated.

17. Will I still enjoy food?
Yes, but it will change. Food becomes… functional. It’s weird. And freeing. You’ll still have your favorites, you just might not need them like before.

18. Is this cheating?
No. It’s a tool. You are still doing the work. You’ve probably done the “try harder” diet thing a thousand times. This is science, not a shortcut.

19. Why do people act weird around me now?
Weight loss changes dynamics. People project their own stuff. Just smile, sip your protein shake, and set boundaries if needed.

20. Will this fix my body image?
Not alone. You need time, reflection, and maybe a therapist. You’ll need to catch your mindset up to your mirror.

INSURANCE, COST, AND LONG-TERM STUFF

21. How much does this cost?
Without insurance? Expensive enough to make you consider bartering family heirlooms. With coverage or coupons, it’s doable, but it varies wildly.

22. How do I get insurance to cover it?
Your doctor may need to submit a prior authorization. Documentation of obesity, comorbidities, or diabetes helps.

23. Will I have to take this forever?
Maybe. Maybe not. Some stay on it for life. Others taper off after hitting goals. It depends on your body, your habits, and your health.

24. Can I regain weight if I stop?
Yes. Without the appetite control, old habits can creep back. Maintenance is a real phase, not the end of the journey.

25. What’s the biggest surprise about being on GLP-1s?
25. What’s the biggest surprise about being on GLP-1s? How emotional the process is. It’s not just about pants size; it’s about healing your relationship with food, your body, and yourself. Also? You now get full from just six bites of chicken and have leftovers for DAYS.How emotional the process is. It’s not just about pants size. It’s about healing your relationship with food, your body, and yourself. Also? That you now get full from six bites of chicken and have leftovers for DAYS.

Final Thoughts: You Asked, I Answered

The GLP-1 journey is wild, wonderful, and at times… a little gassy. Whether you’re here for the science, the side effects, or just someone who gets what it’s like to hide your injection pen from nosey friends snooping in your refridgerator, you’re not alone. I have been where you are. I am where you are. And if you still have questions, keep sending them my way.

I’ll keep answering. Most importantly, I will keep answering honestly, humorously, and without ever telling you to give up carbs. Check it out! Have you streamed our 5-Minute Podcasts available on your favorite streaming services?

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